KMID : 0360220090500121817
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Journal of the Korean Ophthalmological Society 2009 Volume.50 No. 12 p.1817 ~ p.1823
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Multifocal Electroretinography in Retinitis Pigmentosa With Non-recordable Full-field Electroretinography
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Jang Sun-Young
Lim Sang-Hyun Ohn Young-Hoon
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Abstract
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Purpose: To investigate the clinical potential of multifocal electroretinography (mf-ERG) for the evaluation of residual retinal function in retinitis pigmentosa (RP).
Methods: From a group of 41 patients with RP examined for full-field and mf-ERGs, 24 patients were selected in whom the full-field ERGs were non-detectable. Data from the mf-ERGs of this group were reviewed retrospectively. Patients were divided into two groups based on best corrected visual acuity (BCVA); Group A, with a BCVA of less than 0.5, and group B with a BCVA greater than 0.5. The amplitudes and implicit times of Ring 1 and Ring 2 among six concentric rings were measured for comparison between mf-ERG groups.
Results: In the mf-ERGs, the amplitudes of Ring 1 and Ring 2 were reduced and implicit time was delayed in all 48 eyes of 24 patients in whom scotopic and photopic responses were non-detectable in full-field ERGs, whereas, there were no detectable responses in Rings 3 thru 6. There was a greater reduction in amplitude and an increased delay in implicit time in group A.
Conclusions: The mf-ERG can estimate the residual macular function in a group of patients with RP in whom the full-field ERG is non-recordable.
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KEYWORD
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Multifocal electroretinography (mfERG), Retinitis pigmentosa
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